vitamin-a

An aged woman with a stroke of vitamin A cream on her face

What Does Vitamin A Do for the Skin? Types & Be...

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Vitamin A, popularly known as retinoids, carries various benefits when it comes to skincare. From improving premature fine lines to...

What Does Vitamin A Do for the Skin? Types & Be...

DR SABA QUTUB

Vitamin A, popularly known as retinoids, carries various benefits when it comes to skincare. From improving premature fine lines to tackling acne in teens, vitamin A has a multitude of advantages. Ageing is one of the most common concerns where you witness people using vitamin A derivatives.  But knowing vitamin A is essential before incorporating it into your skincare. All vitamin A derivatives are not the same and may or may not work effectively for your daily routine. This blog will deeply introduce you to vitamin A in skincare, its benefits and types, and how you can use it competently.  What is Vitamin A  Vitamin A is a group of fat-soluble compounds that can heavily contribute to our skin's health. They behave with the skin in different ways based on their chemical structure and properties. Retinoic acid is the active form—the one that interacts directly with skin cells. Some of the most well-talked compounds in skincare are; Retinol Retinaldehyde or Retinal Retinyl Esters Retinoic Acid You may confuse vitamin A with retinoids. They are related, but not the same. Vitamin A is an umbrella term for these fat-soluble compounds, and retinoids are the vitamin A derivatives used in dermatology.  Also Read: 10 Facts to Know Before Adding Retinoid to Your Skincare Routine What Does Vitamin A Do For the Skin  Vitamin A can accelerate the cellular renewal in the skin, boost elastin and collagen production, and even out your skin tone. Here's what it can do for your skin in detail; Fight Ageing Signs Whether it is premature signs of ageing like crow's feet or smile lines, or stubborn loose skin, vitamin A derivatives can show a significant difference with the consistent use. Some retinoids, like retinol and retinaldehyde, can induce collagen production, which further helps in making your skin plump and youthful. Research suggests retinoids can help with treating photoageing.  Helps with Acne Vitamin A has the ability to mildly exfoliate the skin and remove dirt, oil, and dead skin cells that can clog your pores to cause acne. The American Academy of Dermatology Association suggests using topical retinoids to manage teen and adult acne.  Fades Dark Spots and Hyperpigmentation Acne scarring, sun spots, or widely spread post-acne hyperpigmentation, retinoids can improve the condition by promoting cellular turnover. Some retinoids can reduce the melanin production and brighten your skin tone.  Improve symptoms of Eczema & Psoriasis Vitamin A, if used in the mild form or low concentration, can provide relief from several skin conditions, including eczema, rosacea, and dermatitis. It can soothe inflammation and aid in associated itching.  Is Vitamin A the Same As Retinol  Vitamin A is a broad term encapsulating different fat-soluble compounds, and retinol is one of them. Retinol, being the most popular vitamin A derivative, is often used interchangeably with vitamin A or even retinoids. But it is not the same as vitamin A.  Popular Vitamin A Forms Used for different purposes, you can find vitamin A in the following popular and easy-to-find forms; Retinol: Retinol needs to be converted into an active form, retinoic acid, before starting its action in the skin; it takes two steps to do so. From unclogging pores to treating wrinkles and sagging skin, retinol is readily available in over-the-counter form in various strengths.  Retinaldehyde: Retinaldehyde is gentler and more potent than retinol and has recently been popular for its mild nature, but it has similar benefits to retinol. It takes just one step to form retinoic acid, which makes it a faster option.  Retinoic Acid: Retinoic acid is already an active form, and it needs no conversion; hence, it plays a crucial role in skincare and the medical industry. Individuals with severe acne, skin conditions like rosacea, and pigmented skin are often prescribed retinoid acid. It cannot be availed in the OTC form.  Retinyl Palmitate: People with sensitive skin have a good alternative. It is mild on the skin, does not aggravate the inflammation, but soothes it. Though it is less potent than retinol, but can improve complexion and texture by contributing to the skin’s elasticity.  While these are the popular vitamin A used in skincare, other forms like adapalene and retinyl acetate hold much value in treating concerns and offer alternative options for those with different skin sensitivities and treatment needs. Vitamin A Skincare Routine  Creating a vitamin A skincare routine is no fuss. You have to be cautious with a few things, and you can get started. We recommend using vitamin A in your nighttime routine, as they are sensitive to sunlight. Be it any vitamin A type.  Begin with a mild, hydrating cleanser that does not dry off the skin. Cream Cleanser can be used to remove makeup, wash away all the dirt, oil, and debris. Its cream-based formula treats your skin softly and nourishes the nutrient-deficient skin. Those looking for a gel-based formula can try Clarifying Cleanser. Apply two to three drops of a vitamin A serum on the face and neck. Don’t rub and let it dry on its own. DRSQ offer Starter Vitamin A for beginners, Miracle Provitamin for intermediate users, and Advanced Vitamin A for experienced ones. Choose a face serum according to your skin type and concern.  Use a moisturiser according to your skin concern and type to lock in the hydration. Hydrafusion has snap-8 peptide infused in a lightweight, luxurious formula to provide anti-wrinkle and anti-dryness benefits. If you are dealing with sensitive skin or inflamed skin, Hydracalm can help with redness and scaling.  Put an end to your routine with an eye serum to target under-eye puffiness, wrinkles, or dark circles. Ensure using serums that have peptides and hyaluronic acid. Best Practices to Use Vitamin A  Let's walk you through some essential tips to get started with vitamin A and use it efficiently.  If you are a beginner with vitamin A, be it any form, start with a low concentration. Don’t use it daily, but a few times a week. This practice helps you to build your skin’s tolerance for vitamin A.  Though some little reactions like flakiness or itching are common, immediately rush to the doctor if these symptoms elevate to the point where you feel unable to bear.  Ensure to apply SPF following the two-finger rule on your face and neck. It protects your skin and does not hinder vitamin A from rejuvenating your skin from within.  Buy a vitamin A serum in an air-tight pack only, as it is sensitive to air, heat, and light. An air-tight packaging ensures the formulation stays stable, preventing oxidation.  FAQs Is vitamin A suitable for acne-prone skin? Yes, vitamin A derivatives like adapalene, retinaldehyde, and tretinoin are effective in treating acne-prone skin. From unclogging pores, preventing breakouts, to speeding cell turnover, they are often recommended to improve the condition.  What is the best age to start using vitamin A? It's a popular misconception that individuals with only mature skin can use vitamin A. But that's not true. Many types of vitamin A are suggested for teen acne and associated conditions. But it should be under the guidance of your doctor. Many experts recommend starting to use vitamin A in your mid-20s when your collagen production begins to decline.  Can I use vitamin A on my sensitive skin? Vitamin A can be used on sensitive skin when taken in the lower strength or gentler form. Retinaldehyde is a milder form than retinol and other derivatives, reducing the chances of irritation, itching, and redness.  Can I layer vitamin A with niacinamide? Yes, combining retinol with niacinamide is generally safe to use. Niacinamide can calm the irritation caused by retinol. If your skin is too reactive, you must ask your doctor before trying on this combination.  References: Bezaleel Mambwe, Kieran T Mellody, Orsolya Kiss, Clare O'Connor, Mike Bell, Rachel E B Watson, Abigail K Langton, "Cosmetic retinoid use in photoaged skin: A review of the compounds, their use and mechanisms of action", 2024 Aug Daniela Milosheska, Robert Roškar, "Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations", 2022 Oct Valerie D Callender, Hilary Baldwin, Fran E Cook-Bolden, Andrew F Alexis, Linda Stein Gold, Eric Guenin, "Effects of Topical Retinoids on Acne and Post-inflammatory Hyperpigmentation in Patients with Skin of Color: A Clinical Review and Implications for Practice", 2021 Nov Siddharth Mukherjee, Abhijit Date, Vandana Patravale, Hans Christian Korting, Alexander Roeder, Günther Weindl, "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety", 2006 Dec

A woman applying retinaldehyde-infused serum to fight fine lines

How’s Retinaldehyde Different From Tretinoin?

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Retinaldehyde and tretinoin, along with other vitamin A derivatives, belong to a class of compounds called retinoids. Whether it’s targeting...

How’s Retinaldehyde Different From Tretinoin?

DR SABA QUTUB

Retinaldehyde and tretinoin, along with other vitamin A derivatives, belong to a class of compounds called retinoids. Whether it’s targeting frown lines, smile lines, or relieving adolescent acne, retinaldehyde and tretinoin are often considered. However, while they share a common origin, they are not created equal. This blog will break down the key differences between retinaldehyde and tretinoin, so we can get to know which one to use and when.  Retinaldehyde & Its Benefits  Retinaldehyde is one of the recently popular vitamin A derivatives that share similar properties to retinol. But it is milder and more potent than retinol – the reason behind its growing fame among skincare enthusiasts. It is a safe option for sensitive skin, reactive skin, and retinoid beginners.  Here are the notable advantages of retinaldehyde; It can vanish your signs of ageing, be they premature, photo-induced, or natural skin ageing. Retinaldehyde can increase the cellular turnover in the skin and boost collagen production.  Individuals struggling with post-acne hyperpigmentation, dark spots, and other marks can find retinaldehyde helpful. It does so by restricting the activity of an enzyme responsible for melanin production, tyrosinase. Retinaldehyde can show significant differences in different types of acne. Moreover, it can also aid acne-scarring and manage oil production. Tretinoin & Its Benefits  Commonly sold under the brand name Retin-A, tretinoin is a vitamin A derivative available only in prescription form. Also known as all-trans retinoic acid, it can also encourage cellular turnover. Tretinoin can be found in 0.05% lotion and solution, 0.1%, 0.05%, and 0.025% cream, and 0.01%, 0.1%, 0.08%, and 0.05% in gel. Topical tretinoin can improve aged-appearing skin. Tretinoin is not as common as other forms of vitamin A, but it has been a proven treatment for the following for decades; Healing cystic acne and can treat both inflammatory and non-inflammatory acne Unclogging pores Gently exfoliating the skin Improving fine lines and wrinkles, and photoageing Hydrating the skin and helping with a rough texture Retinaldehyde Vs Tretinoin: Key Differences  Retinaldehyde takes only one step to get converted into retinoic acid, an active form; thus, you can expect faster results with consistent use. But tretinoin is faster, it is already an active form, retinoic acid, thus requires no conversion to start acting on the concern.  Available in both over-the-counter and prescription forms, retinaldehyde is available in different strengths. While tretinoin can be obtained with a doctor’s prescription only.  Retinaldehyde or retinal is more potent than retinol, but tretinoin is even more potent than both of these.  People struggling with severe acne can be prescribed tretinoin. It also helps with widely spread stubborn pigmentation, along with showing positive results in fighting ageing signs. It can regulate sebum production, hence recommended for oily skin. Whereas retinaldehyde can produce noticeable improvement in signs of ageing, moderate acne, and sensitive skin concerns.  While retinaldehyde is a gentle form, tretinoin can be a little harsh on the skin, especially if you are newly introduced to the ingredient.  Also Read: Adapalene Vs Tretinoin: Comparing Them for Wrinkles, Uses, and Side Effects Tretinoin or Retinal: Which One Should You Use? It might confuse you to choose between tretinoin and retinaldehyde with so many available options and considerations. But if you are aware of your concern, skin type, and sensitivity, you can make an informed decision. Retinaldehyde can favour sensitive skin as it is mild, and tretinoin can be harsher. But for targeted treatments, tretinoin can achieve desirable results.  Moreover, retinaldehyde is easily available in different strengths and does not have any major side effects. If you are to choose for combating ageing, retinaldehyde can be a better choice. But it’s best to consult your doctor for suitable advice and avoid potential risks.  Having said that, tretinoin works effectively for fighting ageing and acne problems. It acts directly as retinoic acid and can help with the skin's texture within a few months.  Is Tretinoin Better Than Retinaldehyde? Both ingredients have their areas of expertise. No one is better than the other. When it comes to dealing with acne and hyperpigmentation, tretinoin can be preferred. On the other hand, retinaldehyde is often suggested for ageing concerns and achieving an even skin tone. People with sensitive skin should opt for retinaldehyde as it is gentler.  How to Start With Retinaldehyde  You must know your skin type and what concerns you are currently facing, then choose a face serum accordingly with a low-strength formulation. Don’t forget to pay attention to the other ingredients in the formula. To help you understand, if you are dealing with fine lines on your dehydrated skin, you can opt for a retinaldehyde product with hyaluronic acid. Start your nighttime skincare routine by washing your face and neck with a mild, soothing cleanser. Get a gel-based or cream-based cleanser, according to your skin’s texture. Then, apply a few drops of retinaldehyde serum.  If you are a beginner, DRSQ’s Starter Vitamin A serum can be your go-to option. It has only 0.25% retinaldehyde to heal your skin without causing irritation or increasing its sensitivity. You can continue with a moisturiser.  Collagen Boost moisturiser is 75% organic with vegan DMAE, MSM, and organic oils to firm and lift the sagging skin. End your routine with Eye Magic overnight recovery night balm to rejuvenate the delicate eye area.  Can I Combine Retinaldehyde With Tretinoin? It’s not recommended to combine both these vitamin A derivatives together, as they can increase the irritation risks along with dryness. Powerful effects of both retinaldehyde and tretinoin can disturb your skin barrier. You can analyse your skin concern and stick to one ingredient rather than mixing the two. Moreover, there is no “need” to use them together.  Key Takeaways  A clear understanding of how retinaldehyde and tretinoin work helps you to set the right goals for your skincare journey. While retinaldehyde can be a mild option, especially if you are a beginner, tretinoin needs a prescription and a targeted approach. Both are effective for achieving results against fine lines, wrinkles, acne and pigmentation.  References: Zoya Siddiqui 1, Alina Zufall 2 3, Marissa Nash 2, Divya Rao 2, Rahim Hirani 2, Marian Russo, "Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review", 2024 Nov  Daniela Milosheska 1, Robert Roškar, "Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations", 2022 Dec  E G Thorne, "Topical tretinoin research: an historical perspective", 1990 Daniela Milosheska 1, Robert Roškar, "Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations", 2022 Dec Siddharth Mukherjee 1, Abhijit Date, Vandana Patravale, Hans Christian Korting, Alexander Roeder, Günther Weindl, "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety", 2006

A girl applying a retinaldehyde serum on her face

Dermatologists’ Approved Best Retinaldehyde Ser...

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Retinaldehyde is a comparatively recently discovered vitamin A derivative that is quite popular to help with, but is not limited...

Dermatologists’ Approved Best Retinaldehyde Ser...

DR SABA QUTUB

Retinaldehyde is a comparatively recently discovered vitamin A derivative that is quite popular to help with, but is not limited to, anti-ageing benefits. It can support the skin's cell regeneration to provide younger-looking skin, and can reduce congestion to prevent blemishes and post-acne hyperpigmentation. Retinaldehyde, commonly called retinal, can function as an oxidant to counteract free radicals, to provide you with anti-ageing benefits for photodamaged skin and help with fine lines, wrinkles, and smile lines. These days, more and more people are turning to retinaldehyde serums, and they’re a great way to incorporate retinaldehyde into your skincare routine. Serums are convenient to carry, come with a non-oily texture, and get absorbed quickly into the skin. But are all retinaldehyde serums the same? The answer is no. So, which retinal serums can you trust? That’s exactly what we’ll discuss in this blog. 1. Starter Vitamin A Serum By DRSQ Starter Vitamin A is a level 1 vitamin A serum, dermatologically tested to reverse topical signs of ageing. It is specifically formulated for the vitamin A beginner, so if you have not tried vitamin A in your life, this is your go-to product to start with. It has 0.25% retinaldehyde, which is non-irritating, boosts the natural cell renewal process, and is able to create volume in dermal tissues.  Retinal is infused with niacinamide to help with sensitivity and hyperpigmentation, tetrapeptide-30 to aid acne lesions and relieve melasma, and ultra-low-weight hyaluronic acid to provide your skin with intense moisture.  Individuals looking for an age-defying serum to fight breakouts, even skin tone, and brighten dull skin can apply two to three drops of the Starter Vitamin A serum on a cleansed face at night and follow with a moisturiser.  2. Miracle ProVitamin Serum By DRSQ When your skin becomes accustomed to the beginner vitamin A, you can move on to a more potent retinoid. One can rely on Miracle ProVitamin serum after using Starter Vitamin A for a few weeks. It has 0.5% retinaldehyde, which can restore the skin's firmness and elasticity. Miracle ProVitamin serum has niacinamide, tetrapeptide-30, and hyaluronic acid for anti-ageing benefits, along with aiding in hyperpigmentation and rosacea.  It regulates the skin, deals with sensitive skin and fine lines and wrinkles. This strength is ideal to enhance the skin's natural defence and restore a luminous and healthy glow. This will be used just like a Starter Vitamin A serum. 3. Advanced Vitamin A Serum By DRSQ If your skin can handle 1% retinaldehyde after getting used to gentler retinoids, Advanced Vitamin A is the serum to switch to. It is backed by the strongest anti-ageing benefits. This serum has a superior formula powered by liposomal retinaldehyde and a completely active biomimetic system to help reduce scar tissue, plump the skin's deeper layers, and fight uneven skin tone.  It can target your ageing symptoms like wrinkles to fine lines more efficiently and deeply. Once your skin builds its tolerance for lower vitamin A strengths, this strength can deliver more lasting results in elasticity.  4. Crystal Retinal 6 By Medik8 Crystal Retinal 6 serum has fast wrinkle-reducing power and delivers improvements in pigmentation, texture, and dullness. Along with retinaldehyde, this serum is formulated with hyaluronic acid to draw and retain moisture to the upper layers of the skin, vitamin E to guard against radical damage, and glycerin to keep your skin nourished and replenished from within. Use this in your evening skincare routine and don’t forget to apply sunscreen the next morning.  5. Very Amazing Retinal By Go-To Skincare Very Amazing Retinal has 0.25% retinaldehyde combined with niacinamide to even out the skin tone and fortifies your skin's barrier, peptides to lift the skin around the mouth, nose, and brows, orobanche extract for keeping your skin healthy and hydrated, and mushroom extract and centella to protect the skin.  Apply one to two pumps on dry skin after cleansing it with a mild cleanser, extending to the neck and chest. Let the serum fully absorb before layering other products. 6. Retinal 0.2% Emulsion By The Ordinary For individuals looking for a high-strength retinaldehyde formula, Retinal 0.2% Emulsion helps in advanced age support. It can fix your textural irregularities and uneven skin tone. Suitable for all skin types, another beneficial ingredient in this emulsion is synthetic oat analogues.  How to Choose the Right Retinal Serum? Choosing the perfect retinaldehyde serum for your skin is a complex task, but there are a few aspects that you must pay attention to.  You should know your skin type, whether it is too sensitive, very dry or oily, to pick the appropriate formulation. Reactive skin may require going with niacinamide and ceramides to soothe it.  For oily and acne-prone skin, you can look for oil-free or non-comedogenic formulas that are made to specifically target blemishes, breakouts and give a refined texture.  If your skin is mature or wrinkled, and you have already used lower-strength retinoid formulations, you can look for higher-concentration formulas with retinaldehyde.  Moreover, look for tight, airless packaging to ensure the product is well protected and maintains its potency over time. How to Use Retinal Serum? If you are new to retinaldehyde, don't use the high-strength formula out of excitement or desperation to get rid of your concerns. This can even worsen your skin condition. Calmness is the key. You can ask your doctor to help you with the recommendation, or you can rely on a good beginner's formula by DRSQ.  Do a patch test and go slow. Apply retinaldehyde lower-strength serum one to two times a week in the nighttime routine and apply the sunscreen the next morning. Once your skin adapts to this new ingredient, you can slowly increase the application frequency.  The Endnote Retinaldehyde is one step closer to the active vitamin A form, that is retinoic acid, so it tends to deliver faster results. Furthermore, retinaldehyde can be suitable for sensitive or reactive skin. It is gentle and mild, may cause less irritation and dryness. Whenever you’re searching for a suitable retinaldehyde serum, you can consider our tips and recommendations in mind, or you can also consult a doctor for the perfect advice. References: Olivier Sorg, Stéphane Kuenzli, Gürkan Kaya, Jean-Hilaire Saurat, "Proposed mechanisms of action for retinoid derivatives in the treatment of skin aging", 2005 Dec Aanand N Geria 1, Christina N Lawson, Rebat M Halder, "Topical retinoids for pigmented skin", 2011 May Andres Cordero, Gladys Leon-Dorantes, Annick Pons-Guiraud, Anonio Di Pietro, Santiago Vidal Asensi, Barbara Walkiewicz-Cyraska, Radek Litvik, Virginie Turlier, Sophie Mery, Christelle Merial-Kieny, "Retinaldehyde/hyaluronic acid fragments: a synergistic association for the management of skin aging", 2011 June

A woman happily applying a retinoid serum on her face

10 Facts to Know Before Adding Retinoid to Your...

DR SABA QUTUB

Very few would dispute that retinoids are among the most utilised and research-backed skincare ingredients that address concerns like acne,...

10 Facts to Know Before Adding Retinoid to Your...

DR SABA QUTUB

Very few would dispute that retinoids are among the most utilised and research-backed skincare ingredients that address concerns like acne, pigmentation, fine lines, and wrinkles. However, alongside popularity, many perpetuated myths are associated with retinoids. These myths are believed by many skincare enthusiasts around the globe and make them hesitant to use retinoids in their skincare.  This blog will bust all popular beliefs related to retinoids in skincare and reveal the truth behind them.  Myth 1 - All retinoids are the same Retinoids are a group of compounds derived from vitamin A. Retinoids come in different forms, ranging in several strengths. You can opt for prescription-strength in oral or topical form or go for the over-the-counter formulations. OTC retinoids are usually gentle on the skin and are used in treating inflammation and wrinkles.  To combat hyperpigmentation, psoriasis and ageing skin, more potent forms would work better. “Retinoid” is an all-catch term that includes many derivatives. While retinol is the most popular, retinaldehyde, retinyl esters, and adapalene have recently started gaining their due. So, not all retinoids are definitely not the same.  Also Read: Retinol Vs Retinaldehyde: What Sets Them Apart? Myth 2 - The stronger the retinoid, the better the outcome It's not at all true that only stronger strengths can provide better results. Even using a smaller concentration consistently can yield reliable results. The truth is that trying higher concentration retinoids without building your skin's tolerance for it can result in moderate to severe side effects like inflammation, irritation, and increased sensitivity. Using stronger formulations as a beginner can be risky and may end up worsening your condition.  Myth 3 - Retinoids make your skin thinner Retinoids can stimulate collagen production in the skin, which is contrary to popular belief that they lead to skin thinning. Some individuals may experience peeling and irritation in the beginning, which backs this myth. This is your skin's way of responding to a completely new ingredient.  The truth is that when a retinoid is applied to the skin in a disciplined skincare regimen, it can thicken the skin by boosting collagen synthesis. This leads to healthier, plumper, and rejuvenated skin.  Myth 4 - You don’t need retinoids until you’re older There is no age bar to using retinoids. People of any age can incorporate retinoid into their skincare routine, depending on their needs. In fact, they were introduced for the treatment of acne in younger individuals. Later on, other benefits of retinoids were discovered, and by the time, it was labelled as "anti-ageing ingredient."  It can treat post-acne hyperpigmentation, sun-damaged skin, blemishes, to several skin conditions like psoriasis. Moreover, retinoids can prevent and treat certain types of skin cancer. So, it would be a mistake to label them as an ingredient only for mature skin.  Myth 5 - Retinoids harm the under-eye skin Skin around the eyes is delicate, thin, and sensitive. Hence, many believe that using retinoids would harm it. There's no truth in this notion. As it turns out, your under-eye area is one of the first regions to get affected by fine lines and retinoids, being the collagen-stimulating ingredient, can smooth them. However, you must be careful with the strength, formulation, and application while choosing a retinoid for your under-eye circles.  Myth 6 - Retinoids exfoliate the skin Retinoids are often regarded as harsh exfoliants, but they are not. They do not behave like chemical exfoliants like glycolic acid, lactic acid, or salicylic acid. But they certainly participate in regulating the cellular turnover to shed old cells and replace them with new ones.  Due to their common side effects of skin peeling and redness, one might assume that exfoliating the skin. But that's a simply false belief.  Myth 7 - People with sensitive skin should not use retinoids Retinoids are thought to be a harsh ingredient and not suitable for sensitive skin types, but that is a misconception. Every sensitive skin is different to each other, and may or may not tolerate retinoid. While they might be a little strong, those with sensitive or reactive skin may adopt a different approach to using them.  One can begin with a lower-strength formula and apply it two to three times a week to assimilate their skin to the formula. Applying moisturiser and sunscreen is non-negotiable.  Myth 8 - Retinoids give fast results  There is nothing like overnight results with using retinoids or any skincare ingredients. Depending upon your skin type, concerns, and formulation you choose, it can take up to a few weeks to several months to deliver results.  In some cases, individuals can start noticing the difference in some weeks only, but that's not the general case. Patience is required to see long-lasting results and healthier skin.  Myth 9 - A pea-sized amount won't work Applying more product does not affect the results. In fact, it can lead to product waste and unwanted side effects like peeling and drying. If you are using a retinoid serum, one to two drops are sufficient for the face and neck. Just ensure you are applying politely and thoroughly. Effective application has nothing to do with a larger amount of product.  Myth 10 - Using retinoids will make your skin red and peel Though there can be some probable reactions in the beginning, those are usually harmless and do not escalate under normal circumstances. This may be your skin's way of adopting retinoids. These effects normally fade away once your skin builds tolerance for retinoids. But considering skin peeling and redness as permanent side effects would be unfair.  How to Start With Retinoids As a beginner, you have to be cautious to avoid unwanted side effects. Begin with a lower-concentration formula; 0.25% would work. Use it one to two times a week in the beginning and slowly boost the usage frequency. Keep noticing how your skin behaves after application. Give your skin proper time to adjust to retinoids before increasing the concentration or application frequency.  Retinaldehyde is more potent and milder than retinol, leading to its increased popularity among users. Your skin can find it easier to tolerate it as a beginner. DRSQ has three formulations as Starter Vitamin A, Miracle ProVitamin, and Advanced Vitamin A for new users, intermediate users, and advanced users, respectively.  Final Words We wanted to dismiss the myths associated with this incredibly effective class of compounds derived from vitamin A, so people won’t take a step back and miss out on the benefits of it.  These myths are man-made and have nothing to do with authentic research or studies. If you struggle with acne, wrinkles, hyperpigmentation, or psoriasis, feel free to start incorporating the right retinoid into your skincare routine. You can talk to your doctor about the concern and get reliable advice.  References: Siddharth Mukherjee, Abhijit Date, Vandana Patravale, Hans Christian Korting, Alexander Roeder, Günther Weindl, "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety", 2006 Neil Sadick, Sukhmani Pannu, Zehara Abidi, Suleima Arruda, "Topical Treatments for Photoaged Skin", 2023 September Ryan R Riahi, Amelia E Bush, Philip R Cohen, Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin", 2026 June Aanand N Geria, Christina N Lawson, Rebat M Halder, "Topical retinoids for pigmented skin", 2011 May Łukasz Szymański, Rafał Skopek, Małgorzata Palusińska, Tino Schenk, Sven Stengel, Sławomir Lewicki, Leszek Kraj, Paweł Kamiński, Arthur Zelent, "Retinoic Acid and Its Derivatives in Skin", 2020 December

A girl in her 30s with premature ageing signs on her face

Retinoids for Ageing Skin: Types, Routine, and ...

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Retinoids have been quite popular among anti-ageing enthusiasts since the 1970s. However, with the latest developments and research, the choices...

Retinoids for Ageing Skin: Types, Routine, and ...

DR SABA QUTUB

Retinoids have been quite popular among anti-ageing enthusiasts since the 1970s. However, with the latest developments and research, the choices have been narrowed. Now, people are looking for specific types of retinoids for their wrinkles and sagging skin.  You may find yourself stuck with brands boasting about their products being the best, but they still make no difference in the skin. It's because before you shop for retinoids, you must know how they work, and which retinoid type would work for your ageing skin.  In this blog, we will explore retinoid types and their effectiveness for anti-ageing skincare, so it will help you find out the best option for you.  What are Retinoids Retinoids are vitamin A derivatives, used to treat acne, ageing concerns, and skin conditions like psoriasis and pigmentary disorders. They can reduce inflammation and have a role in cell growth regulation. Structurally, retinoids are similar to vitamin A. They are available in both over-the-counter (for weaker forms) and prescription-strength formulations (for stronger forms). Both oral and topical retinoids can make significant differences in your skin conditions, depending on how disciplined you are, given that you are taking the right type of retinoid.  Retinoids for Anti-Ageing Your skin experiences collagen loss as you age. Collagen is an essential protein that contributes to youthful skin, plumpness, and texture. Another concern for the ageing skin is reduced cellular turnover. Cellular turnover is the skin's regeneration process through which it sheds old cells and replaces them with new ones. Both these factors result in ageing signs like wrinkles, fine lines, sagging skin, crow's feet, and smile lines.  Here comes the role of retinoid in your ageing skin. Retinoids can help with new collagen production and slow down the degradation of collagen that is already present in the skin. Free radicals can contribute to damaged skin collagen. Retinoids neutralise them, help with inflammation, and irritation.  Which Retinoid is the Best for Anti-Ageing When it comes to targeting ageing signs, six major types of retinoids stand out. Retinol This is the most heard-about and commonly used vitamin A derivative among the family. Found in OTC retinoid products like serums and moisturisers, retinol enhances proliferation.  Retinaldehyde Also known as retinal, retinaldehyde is a better alternative for OTC retinol. It's potent and mild on the skin, may suit sensitive skin types, and targets ageing and photoageing. Adapalene Another OTC and affordable retinoid, primarily used to treat acne, but may help with premature ageing signs. With the consistent use, it can smooth out your skin's texture and roughness.  Tretinoin Available with prescription, this retinoid works well with skin types already used retinol and desire a strong anti-ageing support.  Retinyl Palmitate This form is considered a mild option, making it suitable for sensitive or very dry skin. It is gentler than retinol and helps reduce mild ageing signs.  Tazarotene You can get this retinoid with a prescription only. It helps with wrinkle reduction, inflammation, and several conditions, including acne and psoriasis. It's a strong acid and reacts with the skin, if not well-tolerated with the stronger retinoids.  Which One Should You Use When it comes to treating wrinkles, every retinoid is unique for each skin type and concern. While retinol is the most commonly used retinoid, your skin may or may not be able to tolerate this powerful vitamin A derivative.  Retinaldehyde or retinal is a gentler alternative than prescription-strength retinoids like tretinoin and more potent than retinol, and could be compatible with your skin. Moreover, it has a closer proximity to the active form of vitamin A and tends to maintain its effectiveness for a longer period than retinol.  Also Read: Retinol vs Retinaldehyde: What Sets Them Apart? The right retinoid is not one-size-fits-all. Pick your retinoid type based on your skin type, concern, and your skin's tolerance.  How to Introduce Retinoids In Your Skincare Understand your skin type, concern, and its intensity. It’s highly recommended to consult your doctor before adding any retinoid to your skincare regimen. Begin with a low concentration. Regardless of the low-concentration product you choose, a patch test is unavoidable.  To test the product, take a tiny amount and apply it to your jawline on alternate nights. Seal with a moisturiser. Observe your skin for irritation, peeling, or any kind of noticeable difference. If your skin behaves good, you can add the product into your routine.  In the beginning, keep your application frequency up to two to three times a week. Increase it gradually as your skin builds its tolerance for retinoid. Use them at night only, as retinoids can increase your skin’s sensitivity to UV light. Apply a broad-spectrum sunscreen during the day. 3 Strengths of Retinoid Serums With Retinaldehyde DRSQ has 3 strengths of retinaldehyde to target all aspects of mature skin, reverse topical signs of ageing, and loose skin. They are formulated with powerful actives like niacinamide to calm sensitive skin, regulate oil production, and fade post-acne hyperpigmentation  tetrapeptide-30 to reduce acne lesions and improve melasma and hyaluronic acid to deeply hydrate the skin.  Wash your skin with any of the cleansers of your choice. Take two to three drops of the retinaldehyde serum and apply all over the face and neck. Cap off your regimen with a moisturiser.  Starter Vitamin A with 0.25% retinaldehyde: This serum is made for retinoid beginners. It’s a low-strength vitamin A and eases your skin to retinoid use.  Miracle Provitamin Serum with 0.5% retinaldehyde: If your skin has already built up retinoid tolerance, this can be a go-to option.  Advanced Vitamin A Serum with 1% retinaldehyde: This is a higher concentration for skin well-tolerated with retinoids.  Retinoids Side Effects Retinoids are powerful ingredients but come with some drawbacks, which are potential side effects. If you are new to them, you may have to face mild irritation, to little redness and burning. But these effects subside as your skin gets familiar with the ingredient. Some retinoids can also first aggravate your acne before treating it.  The other common side effects include; Dryness Flakiness Roughness Purging Peeling Sensitivity to sunlight Inflammation Is Retinoid the Same as Retinol No, retinoid is not the same as retinol. Retinoid is an umbrella term, refers to the vitamin A derivatives, and retinol falls under it. Retinol is a type of retinoid that is primarily identified as an anti-ageing ingredient around the world.  Are All Retinoids the Same No two retinoids are exactly the same. They all belong to the vitamin A family but differ in terms of strength, conversion, side effects, and potency. Retinoids include both over-the-counter such as retinaldehyde, retinol, and retinyl palmitate, and prescription-based options like adapalene and tretinoin. Each retinoid has its own unique identity and usage, and is used for several skin concerns apart from ageing.  Key takeaways Retinoids belong to the vitamin A family and are popularly used to treat ageing problems, including fine lines, wrinkles, and loose skin.  They stimulate cellular turnover and collagen production to make skin youthful and even.  While retinol is the most popular, retinaldehyde is a milder alternative and beginner-friendly.  There is no universal retinoid to work for everyone. Choose your retinoid according to your skin type, concern, and skin tolerance.  As a beginner, start with a lower-concentration formulation. Observe your skin's behaviour towards the ingredient and then slowly increase the application count.  From dryness, flakiness, to rough patches, inflammation and burning, retinoids can have mild to severe side effects on the skin. A patch test is necessary before use.  References: American Academy of Dermatology Association. Retinoids: What They Are and How to Use Them. Clinical Interventions in Aging, 1(4), 327–348. Archives of Dermatology, 143(5), 606–612. Improvement of naturally aged skin with vitamin A (retinol). Arch Dermatol, 143(5), 606–612. Retinoids and their utility in dermatologic therapy. Clinics in Dermatology, 38(6), 661–665. Journal of the American Academy of Dermatology, 45(5), S68–S76. Journal of Dermatological Science, 98(3), 186–192.

A woman applying an Adapalene (Differin) serum on her face to fight wrinkles

Adapalene Vs Tretinoin: Comparing Them for Wrin...

DR SABA QUTUB

Retinoids are often the first choice for anti-wrinkle treatment seekers owing to their substantial scientific validation. Vitamin A derivatives like...

Adapalene Vs Tretinoin: Comparing Them for Wrin...

DR SABA QUTUB

Retinoids are often the first choice for anti-wrinkle treatment seekers owing to their substantial scientific validation. Vitamin A derivatives like retinol and retinaldehyde have already gained much exposure in anti-ageing concerns, and lesser-known but highly effective options, such as adapalene and tretinoin, have started being discussed recently.  Adapalene (commonly known by the brand name Differin) and Tretinoin (known by brand names like Retin-A) are good topical retinoids with scientifically based evidence to fight ageing signs on the skin. But what is the difference between them, and which one among them should you use? In this blog, we will explore adapalene vs tretinoin and their proper application to combat ageing problems.  Retinoids for Anti-Ageing Retinoids are proven to treat skin problems, primarily ageing, acne, and other skin conditions like psoriasis. They do so by stimulating the collagen production in your body that lessens the signs of ageing and makes your skin look younger, firmer, and youthful. The most commonly used retinoid for ageing concerns is retinol, but now retinaldehyde is also gaining popularity due to its higher potency and better efficacy.  Retinaldehyde is gentler than retinol and considered beginner-friendly. DRSQ has three strengths of serums of retinaldehyde as 0.25% Starter Vitamin A serum, 0.5% Miracle Pro Vitamin serum, and 1% Advanced Vitamin A serum for beginners, intermediate, and advanced users.  What is Adapalene Adapalene is a type of retinoid among the third generation, and it is popular for treating different acne types and skin conditions like rosacea, psoriasis, and keratosis pilaris. However, studies suggested that it can show significant improvements in skin photoageing (or ageing due to long-term sun exposure) when used in the 0.3% gel form, making it an effective option for ageing skin.  You can find it in different forms and formulations, including gels, creams, and lotions. The commonly available strengths are 0.1% and 0.3%. It works by increasing the collagen production and stimulating the new blood cell production in the skin, which results in fewer fine lines and dark spots.  What is Tretinoin Tretinoin is a retinoid form, widely sold under the brand name Retin A, and also called all-trans retinoic acid. Tretinoin can help in several skin problems like hyperpigmentation, bumpy and rough skin, and wrinkles by encouraging the cellular turnover. It helps in unblocking the blocked pores and improving the skin's texture.  Available in different forms like creams, lotions, gels, and liquid solutions, tretinoin can be found in 0.05% lotion and solution, 0.1%, 0.05%, and 0.025% cream, and 0.01% and % in gel. It is not available in an over-the-counter option and can only be taken with your doctor’s prescription.  Adapalene Vs Tretinoin for Wrinkles Both tretinoin and adapalene are retinoids, but behave differently with your skin. Moreover, from formulations to forms and available strengths, they vary. They have both been noted to fight wrinkles. But if your skin is sensitive, you must check with your doctor before using any of them. Research was conducted in 2018 for more than 24 weeks on over 100 individuals to study the efficacy of both adapalene and tretinoin to reduce the effects of sun-induced ageing, including wrinkles. 0.3% adapalene and 0.05% tretinoin were used to reduce wrinkles. The study revealed both adapalene and tretinoin as effective anti-ageing ingredients.  While they cannot entirely reverse your ageing, they boost the collagen and elastin levels in your skin to help smooth wrinkles and fine lines.  Adapalene (Differin) Tretinoin (Retin-A) Type Third-generation synthetic retinoid First-generation natural retinoid (all-trans retinoic acid) Common Brand Names Differin Retin-A FDA Availability Available over-the-counter (0.1%) and prescription (0.3%) Prescription-only Uses Acne, rosacea, psoriasis, keratosis pilaris, wrinkles & and fine lines Acne, wrinkles, hyperpigmentation, and skin texture Suitability for Sensitive Skin Gentler, better tolerated by sensitive skin Can be harsher; requires slower skin adjustment Formulations Available Gel, cream, lotion Cream, lotion, gel, liquid Side Effects Mild irritation, dryness, peeling (especially initially) Similar: irritation, dryness, peeling, redness Usage Timing Nighttime use only Nighttime use only Sun Sensitivity Increases sensitivity to the sun. Use sunscreen daily Increases sensitivity to the sun. Use sunscreen daily Which One Should You Use for Your Wrinkles? One approach may not work for everyone when it comes to deciding between adapalene and tretinoin. Your skin condition, intensity of your concern, skin type, and medical conditions can play a major role. It's best to consult your dermatologist to learn the best choice for you.  Tretinoin may work faster when it comes to anti-ageing, specifically wrinkles and fine lines. Adapalene can take a little longer. But both of them show similar results and are almost equally effective for wrinkle treatment induced by sun damage. If you struggle to address wrinkles for sensitive skin, adapalene could be easier on the skin as it is less likely to irritate reactive skin. Whereas, your skin may require more time to get accustomed to tretinoin and can be slightly more abrasive on the skin.  Can You Use Adapalene and Tretinoin Together Using adapalene and tretinoin together may not be a smart idea, as they both possess similar benefits and side effects. What you can do is to decide on one ingredient among them and be consistent to see effective results. Combining them can increase the chances of potential irritation, excessive dryness, and peeling, regardless of your skin type.  How to Use Adapalene or Tretinoin for Wrinkles  Adapalene and tretinoin are retinoids. So they will be used in the same way as retinoid products.  If you are new to retinoids, begin with a low concentration product. 0.1% adapalene or 0.01%, 0.02%, or 0.025% tretinoin potency would work. This will allow your skin to build its tolerance for retinoids. Always do a patch test while trying on a new product.  Apply adapalene or tretinoin at night. Retinoids can increase your skin's sensitivity towards the sun. Use them in your nighttime skincare routine. Ensure to apply sunscreen before going out in the sun to enhance protection.  Once your skin gets used to the product, you can increase the application frequency.  Avoid mixing or combining your product with AHAs, BHAs or benxoyl peroxide without consulting your doctor.  Tretinoin and Adapalene: Side Effects These two ingredients can cause similar side effects on the skin. Some individuals may experience little itching and stinging because they are new to retinoids. These symptoms usually don't worsen over time but tend to decrease with the continued use as your skin becomes used to the ingredient.  However, in some cases, these side effects may become unbearable and may cause skin damage. This can happen due to several reasons, like you have not chosen the right concentration or retinoid type. In such a scenario, stop the retinoid usage immediately and seek your doctor's help.  The frequently observed side effects are; Inflammation Redness Burning Stinging Peeling  Dryness, roughness Scaling Skin darkening Skin lightning Conclusion Both adapalene and tretinoin can be used to treat wrinkles and other signs of ageing. Adapalene may take a little longer to show significant differences in your loose skin, and it interacts gently with your skin. Your skin may find tretinoin harsher, irritating, but it can be quicker to drive outcomes. Observe your skin behaviour after incorporating any of them into your skincare routine.  References: John Waugh, Stuart Noble, Lesley J Scott, "Adapalene: a review of its use in the treatment of acne vulgaris", 2004 B A Bernard, "Adapalene, a new chemical entity with retinoid activity", 1993 Zoya Siddiqui, Alina Zufall, Marissa Nash, Divya Rao, Rahim Hirani, Marian Russo "Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review", 2024 November E G Thorne, "Topical tretinoin research: an historical perspective", 1990 J S Weiss, C N Ellis, J T Headington, J J Voorhees, "Topical tretinoin in the treatment of aging skin", 1998 July