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SNAP-8 Peptide: Wrinkle reduction without Needles

SNAP-8 Peptide: Wrinkle reduction without Needles

Wrinkles are caused overtime due to repeated contraction of the muscle involved in facial expression, SNAP 8 Peptide reduces the depth of wrinkles on the face without the use of needles, let’s learn how.

We get expression lines and wrinkles in locations of repeated facial movements such as around the mouth (laugh lines), around the eyes (crows’ feet), lines on forehead and frown lines between eyebrows.

For muscles to contract, a neuromuscular transmitter called acetylcholine must be released from the cells known as Synaptic Vesicles. Synaptic vesicles are located inside the nerve supplying the muscle. The Synaptic vesicles needs to be docked onto the membrane (border of the neuron) to release Acetylchilone. Acetylcholine then binds to the muscle receptors and trigger a cascade of steps which leads to muscle contraction. More the acetylcholine, stronger the muscle contraction resulting in deeper lines overtime.

So, how can we stop the acetylecholine to be released from the synaptic vesicles. When muscles get a signal of expression, it triggers the binding of protein called Snap 25 to protein called VAMP and Syntaxin and forming a SNARE complex. SNARE is a temporary complex that mediats the docking of Synaptic vesicles to nerve memebrane which then releases Acetylcholine. What if we could block this pathway?

This is how anti-wrinkle injections consisting botulinum toxins work. They block this pathyway and stops the release of acetylcholine which in turns stop the muscle contraction.

SNAP-8 does what botulinum toxin does, but without the need of a needle. SNAP-8 mimics Snap 25 (the protein used in forming a SNARE complex) and competes with SNAP-25 for a position in the SNARE Complex, thereby modulating its formation. This destabilises the SNARE complex and the vesicle can not release Acetylcholine efficiently and therefore muscle contraction is reduced , preventing the formation of lines and wrinkles.

- Studies have shown that by reducing muscle contractions with SNAP-8, wrinkle depth is reduced by up to 21% in the first seven days, and up to 63% in one month of treatment.

- Fine lines and expression wrinkles reduce with continuous use, and the face looks smoother. It It is perfect for mature skin and is safe for sensitive skin.

– Reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.

Our anti-ageing moisturiser, HYDRAFUSION is formulated with SNAP-8 Peptide Solution. Use it morning and night and overtime notice visible reduction in fine lines and wrinkles.

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